All You Need to Know About Drug Use in Pregnancy
The Food and Drug Administration (FDA), which is the highest authority in the U.S. for drugs and their use, ALLIED ALL CATEGORIES TO 5 CATEGORIES FROM THEIR RISKS TO USE DURING PREGNANCY.
According to this classification accepted all over the world, medicines are in a category ranging from safe (category A) to more risky (category x). This classification is made according to the data obtained from human and animal experiments lasting many years.
Category A: Controlled studies in pregnant women, drugs that have not been shown to pose any risk to the fetus when used in the first 3 months of pregnancy. There is no evidence that the drug is harmful in later periods. These drugs can be used safely during pregnancy.
Category B: Drugs in this category fit one of two conditions: 1- The harmful effects of drugs in animals have not been shown, but clinical experience is insufficient in pregnant women. 2- Studies in experimental animals have shown the toxic effect of the drug on the fetus, but controlled studies in pregnant women have not confirmed the fetotoxic effect. These drugs can be used during pregnancy if necessary.
Category C: Medicines in this category fit one of two conditions: 1- The harmful effects of drugs have been shown in animals, but clinical experience is insufficient in pregnant women. 2- The drug has not been studied in experimental animals or pregnant women. These drugs should be used if it is believed that the benefit of the drug to the pregnant woman will be greater than the potential harm to the fetus.
Category D: The harmful effect of drugs in this category on human fetus has been proven. In case of using the drug in this category, if the mother and the fetus will be faced with greater risks, it should be used by explaining the potential risk to the mother candidate in detail, considering the benefit-loss ratio.
Category X: The drugs in this category have been shown to be harmful to the fetus in the examination of animals and pregnant women. Drugs of Category X should never be used in pregnant women and those who are likely to become pregnant.